From experiments by Foe and von Dassow (Foe, V.E., and G. von Dassow. 2008. J. Cell Biol. 183:457–470) and others, we infer a molecular mechanism for positioning the cleavage furrow during cytokinesis. Computer simulations reveal how this mechanism depends on quantitative motor-behavior details and explore how robustly this mechanism succeeds across a range of cell sizes.
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机译：根据Foe和von Dassow的实验（Foe，V.E。和G. von Dassow。2008. J. Cell Biol。183：457-470）和其他实验，我们推断出在胞质分裂过程中定位卵裂沟的分子机制。计算机仿真揭示了该机制如何依赖于定量的运动行为细节，并探索了该机制在各种细胞大小范围内如何成功实现鲁棒性。
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